Since 2001, Dirty Heads have blended hip-hop, reggae, and rock to create a distinctive sound that reflects their Southern California roots and resonates with audiences worldwide. Their global popularity soared in 2021 when the song "Vacation" (initially released in 2017) gained over six billion views and streams through the widely embraced #VacationTransition challenge on TikTok. This challenge organically originated from users on the social media platform.

In 2021, Dirty Heads released "The Best Of Dirty Heads" compilation, featuring a new collaboration with Travis Barker and Aimee Interrupter of The Interrupters. This compilation showcases the band's diverse musical style and highlights their ability to connect with audiences across different genres. Dirty Heads' fusion of musical elements and their engagement with social media trends have contributed to their enduring popularity and recognition in the music industry.